Anti-leukemic effects investigation of alpha-mangostin: apoptotic induction and synergistic potential with chemotherapeutic drugs, molecular targets in leukemic cell lines and bone marrow-derived acute leukemic cells

Background Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) remain challenging to treat because of treatment-related toxicity, drug resistance, and disease relapse. Alpha-mangost...