{"contract_version":"web-product-v1","provenance":{"source_url":"https://link.springer.com/article/10.1186/s12906-026-05672-0","content_hash":"916f1f38c7b75fc28337be59f411dc1463b31de25698efdcb766e9a7a0a701e1","story_version":1,"source_revision":null,"source_revision_status":"NOT_RECORDED_IN_PUBLIC_STORY_SCHEMA","publication_updated_at":"2026-11-13T05:51:48Z","published_at":"2026-11-13T00:00:00+00:00","hash_scope":"RECORDED_ARCHIVE_HASH_NOT_VERIFIED_ORIGINAL_BYTES"},"corrections":{"status":"PENDING_EVIDENCE","versions":[],"reason":"PUBLIC_CORRECTION_PUBLICATION_CONTRACT_REQUIRED"},"living_event":{"status":"PENDING_EVIDENCE","sources":[],"claims":[],"evidence":[],"counterevidence":[],"timeline":[],"uncertainty":[],"relations":[],"reason":"AUTHORIZED_PUBLIC_CHILD_PUBLICATION_CONTRACT_REQUIRED"},"analysis":{"contract_version":"web-product-v1","status":"PENDING_EVIDENCE","sections":[],"required_section_count":12,"section_slots":[{"section_id":1,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":2,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":3,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":4,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":5,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":6,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":7,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":8,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":9,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":10,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":11,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":12,"status":"MISSING_APPROVED_REPORT_DATA"}],"source_story":{"story_id":213499,"version":1,"content_hash":"916f1f38c7b75fc28337be59f411dc1463b31de25698efdcb766e9a7a0a701e1"},"approved_heading_mapping":"PENDING_EVIDENCE","depth":null,"reason":"APPROVED_ANALYSIS_PUBLICATION_AND_HEADING_CONTRACT_REQUIRED"},"story":{"story_id":213499,"title":"Immunomodulatory effects of fractions from Aframomum melegueta K.Schum. and Xylopia aethiopica (Dunal) A.Rich. on cytokine responses in PBMCs from individuals with hyperreactive onchocerciasis​","summary":"Background Hyperreactive onchocerciasis (HO) is characterized by a severe skin inflammation. We previously showed that hydro-ethanolic crude extracts of Aframomum melegueta K.Schum. (AM) and Xylopia aethiopica (Dunal) A.Rich. (XA) possess anti-helminthic activities and exhibit Th2 and Th17 anti-inflammatory responses on peripheral blood mononuclear cells (PBMCs) from HO individuals. However, the specific bioactive fraction of the plant extracts that carries this activity remain unknown. This stu","category":"fitoterapi","country":"","published_at":"2026-11-13T00:00:00+00:00","source_url":"https://link.springer.com/article/10.1186/s12906-026-05672-0","language":"en","status":"PUBLISHED","version":1,"content_hash":"916f1f38c7b75fc28337be59f411dc1463b31de25698efdcb766e9a7a0a701e1","subcategory":"","image_url":null,"publication_updated_at":"2026-11-13T05:51:48Z","degree":"D3","source_language_status":"KNOWN","masa_classification_status":"RECORDED","spam_assessment_status":"RECORDED","source_language":"en"},"entities":[],"related":[],"timeline":[],"evidence_visibility":"PENDING_PUBLICATION_CONTRACT","living_event_status":"PENDING_AUTHORIZED_API_CONTRACT"}