{"contract_version":"web-product-v1","provenance":{"source_url":"https://link.springer.com/article/10.1186/s12906-026-05669-9","content_hash":"c08f391a2672780b1538291aca2e388d1b4d38d595519828d5533e2834e8be02","story_version":1,"source_revision":null,"source_revision_status":"NOT_RECORDED_IN_PUBLIC_STORY_SCHEMA","publication_updated_at":"2026-11-13T08:52:05Z","published_at":"2026-11-13T00:00:00+00:00","hash_scope":"RECORDED_ARCHIVE_HASH_NOT_VERIFIED_ORIGINAL_BYTES"},"corrections":{"status":"PENDING_EVIDENCE","versions":[],"reason":"PUBLIC_CORRECTION_PUBLICATION_CONTRACT_REQUIRED"},"living_event":{"status":"PENDING_EVIDENCE","sources":[],"claims":[],"evidence":[],"counterevidence":[],"timeline":[],"uncertainty":[],"relations":[],"reason":"AUTHORIZED_PUBLIC_CHILD_PUBLICATION_CONTRACT_REQUIRED"},"analysis":{"contract_version":"web-product-v1","status":"PENDING_EVIDENCE","sections":[],"required_section_count":12,"section_slots":[{"section_id":1,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":2,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":3,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":4,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":5,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":6,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":7,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":8,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":9,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":10,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":11,"status":"MISSING_APPROVED_REPORT_DATA"},{"section_id":12,"status":"MISSING_APPROVED_REPORT_DATA"}],"source_story":{"story_id":214425,"version":1,"content_hash":"c08f391a2672780b1538291aca2e388d1b4d38d595519828d5533e2834e8be02"},"approved_heading_mapping":"PENDING_EVIDENCE","depth":null,"reason":"APPROVED_ANALYSIS_PUBLICATION_AND_HEADING_CONTRACT_REQUIRED"},"story":{"story_id":214425,"title":"Anti-leukemic effects investigation of alpha-mangostin: apoptotic induction and synergistic potential with chemotherapeutic drugs, molecular targets in leukemic cell lines and bone marrow-derived acute leukemic cells","summary":"Background Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) remain challenging to treat because of treatment-related toxicity, drug resistance, and disease relapse. Alpha-mangostin, a xanthone derivative from Garcinia mangostana, has demonstrated anticancer and pro-apoptotic activities in several experimental models. This study investigated the cytotoxic and apoptosis-associated effects of alpha-mangostin in acute leukemic cells and its interaction with daunorubicin. Methods C","category":"fitoterapi","country":"","published_at":"2026-11-13T00:00:00+00:00","source_url":"https://link.springer.com/article/10.1186/s12906-026-05669-9","language":"en","status":"PUBLISHED","version":1,"content_hash":"c08f391a2672780b1538291aca2e388d1b4d38d595519828d5533e2834e8be02","subcategory":"","image_url":null,"publication_updated_at":"2026-11-13T08:52:05Z","degree":"D3","source_language_status":"KNOWN","masa_classification_status":"RECORDED","spam_assessment_status":"RECORDED","source_language":"en"},"entities":[],"related":[],"timeline":[],"evidence_visibility":"PENDING_PUBLICATION_CONTRACT","living_event_status":"PENDING_AUTHORIZED_API_CONTRACT"}